Epoxidizing arenes
نویسندگان
چکیده
منابع مشابه
Palladium-Catalyzed Acetylation of Arenes
A simple method for the preparation of aryl methyl ketones is reported. The transformation involves the Pd-catalyzed coupling of an acyl anion equivalent, acetyltrimethylsilane, with aryl bromides to afford the corresponding acetylated arenes in synthetically useful yields. The methodology is tolerant of heterocycles and provides a new method for arene functionalization.
متن کاملEnforced stacking in crowded arenes.
Disk-shaped π-surfaces that stack to form columnar structures1 are prototypes of molecular-scale wires that have an insulating hydrocarbon sheath surrounding a conductive aromatic core.2 Typically, the strengths of the associations between the molecules, formed through contacts between aromatic surfaces, are weak. Previous schemes to modulate these strengths are based on metalligand interaction...
متن کاملCu(I)-mediated (18)F-trifluoromethylation of arenes: rapid synthesis of (18)F-labeled trifluoromethyl arenes.
This report is concerned with an efficient, Cu(I)-mediated method for the radiosynthesis of [(18)F]trifluoromethyl arenes, abundant motifs in small molecule drug candidates and potential radiotracers for positron emission tomography. Three (18)F-labelled radiotracer candidates were synthesised from [(18)F]fluoride ions as proof of principle. The new protocol is widely applicable for the synthes...
متن کاملThe catalytic cross-coupling of unactivated arenes.
The industrially important coupling of aromatic compounds has generally required differential prefunctionalization of the arene coupling partners with a halide and an electropositive group. Here we report that palladium, in conjunction with a copper oxidant, can catalyze the cross-coupling of N-acetylindoles and benzenes in high yield and high regioselectivity across a range of indoles without ...
متن کاملIodine-catalyzed ammoxidation of methyl arenes.
The development of organic transformation using cheap and readily available substrates under mild conditions will be pivotal for green and sustainable synthetic organic chemistry. Concerning our continued interest in the cyanation reaction, a metal-free direct ammoxidation of readily available methyl arenes leading to nitriles was established under mild conditions. A series of aryl methanes esp...
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ژورنال
عنوان ژورنال: Science
سال: 2020
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.368.6494.962-e